منابع مشابه
Differential sensitivity of chromium-mediated DNA interstrand crosslinks and DNA-protein crosslinks to disruption by alkali and EDTA.
Some compounds of hexavalent chromium are well-established carcinogens. Chromium enters mammalian cells in the hexavalent form and is reduced to chromium (III). Treatment of purified DNA with chromium (III) produces DNA-DNA interstrand crosslinks (DDC) which obstruct the progression of DNA polymerases in vitro. DDC were also detected in chromate-treated cultured normal human lung cells using th...
متن کاملHow to Fix Exponential Backoff
Randomized exponential backoff is a widely deployed technique for coordinating access to a shared resource. A good backoff protocol should, arguably, satisfy three natural properties: (i) it should provide constant throughput, wasting as little time as possible; (ii) it should require few failed access attempts, minimizing the amount of wasted effort; and (iii) it should be robust, continuing t...
متن کاملHow to fix the gauges?
We present a special constraint structure that possesses both reducable and chain structure. Using our constraint structure, we show that the number of required gauge fixing conditions is just equal to the number of chains and the remaining requirements follow from consistency conditions. Electrodynamics and Yang-Mills theories are discussed as examples. e-mail address: [email protected] e-m...
متن کاملHigh-LET irradiation of a DNA-binding protein: protein-protein and DNA-protein crosslinks.
The chromosomal protein MC1 is a monomeric protein of 93 amino acids that is able to bind any DNA but has a slight preferential affinity for some sequences and structures, like cruciform and minicircles. The protein has been irradiated with 36Ar18+ ions of 95 MeV/nucleon. The LET of these particles in water is close to 270 keV/microm. We tested the activity of the protein by measuring its abili...
متن کاملHow to fix the obesity crisis.
If current trends continue, an excess of weight will surpass smoking as the primary cause of preventable deaths in the U.S. Health experts, however, often overlook the best near-term strategy for stopping the obesity epidemic: behavior modification methods that have been shown to change people's eating and exercise habits. Illustration by Bryan Christie. Although science has revealed a lot abou...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: DNA Repair
سال: 2020
ISSN: 1568-7864
DOI: 10.1016/j.dnarep.2020.102924